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NAD+ – 600mg

The full form of NAD is  Nicotinamide Adenine Dinucleotide,  an essential coenzyme present in the cells of all living organisms. In energy metabolism and cellular signaling, NAD+ plays a crucial role. Across metabolic pathways, NAD+ also supports redox reactions.

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NAD+ 600 Mg

NAD+ stands for “Nicotinamide Adenine Dinucleotide,” which is a research peptide studied for its potential role in aging, mitochondrial function, metabolism, and neuroprotection.

It was first discovered by two scientists, Arthur Harden and William John Young, in 1906 during their work on yeast fragmentation. 

Moreover, NAD+ also naturally exists in every cell of the body, as stated by the study mentioned by the Cleveland Clinic on NAD+.  The naturally existing NAD+ plays an important role in the body including keeping the muscle, brain, and heart healthy. If NAD+ did not exist in our bodies, we would not be able to convert food into energy, move our muscles, or even stay alive. 

At Orion Peptides, we sell NAD+ 600mg at affordable prices to researchers and scientists for their lab studies.

Note: All the products we sell at Orion Peptides are only for research purposes and strictly not for human consumption. Also, NAD+ is currently not approved by the FDA. 

Mechanism of Action (NAD+)

In laboratory research, NAD+ is studied for its role in cellular energy production. It works as an electron carrier inside cells.  Researchers observe this process during glycolysis, the TCA cycle, and oxidative phosphorylation. These processes help produce ATP inside mitochondria. NAD+ also changes between two forms called NAD+ and NADH. This cycle helps maintain cellular energy balance and supports normal metabolic activity. Researchers also study NAD+ because it interacts with several important enzymes in cells.

1. Sirtuins (SIRT1–7)

SIRT1–7 enzymes are linked with gene expression, mitochondrial function, inflammation, and cellular stress responses.

2. PARPs

PARPs are involved in DNA repair and cellular maintenance processes.

3. CD38 and SARM1

These enzymes are studied for their role in calcium signaling and immune-related cellular activity.

Is NAD+ a Peptide?

Most people consider NAD+ to be a peptide. However, NAD+ is not a peptide but a coenzyme. It is composed of two nucleotides, including nicotinamide riboside diphosphate and adenosine monophosphate, joined by their phosphate groups and functions as an essential electron carrier. 

Chemical Structure of NAD+

Chemical details include:

1. Molecular formula:

C₂₁H₂₇N₇O₁₄P₂

2. Molecular weight:

663.43 g/mol

3. CAS number:

53-84-9
  1. PubChem CID:
925

Who Should Buy NAD+ 600mg?

NAD+ 600mg is for research use only. It is not for human consumption. It is mainly used by researchers and laboratory professionals who are studying cellular energy and metabolism. It is suitable for those who are working on:
  • Cellular energy production studies
  • Mitochondrial function research
  • Aging and longevity-related research models
  • DNA repair and cellular stress response studies

Different Variations of NAD+ At Orion Peptides

At Orion Peptides, we provide three different variations of NAD+ to buy for research purposes. These include:
  1. NAD+ 100mg
  2. NAD+ 500mg
  3. NAD+ 600mg

Disclaimer:

NAD+ is an investigational research compound. It is intended only for in vitro and animal research. It is not approved by the FDA or EMA for human use. Regarding safety or efficacy in humans, no claims are made, and preclinical findings do not predict clinical outcomes. Products may carry risks related to impurities or immune reactions. Use NAD+ only in qualified research facilities. Institutional oversight is required. All materials are sold strictly for laboratory research purposes

References Studies:

  1. https://my.clevelandclinic.org/health/body/nad-nicotinamide-adenine-dinucleotide
  2. https://en.wikipedia.org/wiki/Poly_(ADP-ribose)_polymerase
  3. https://en.wikipedia.org/wiki/Sirtuin
  4. https://teachmephysiology.com/biochemistry/atp-production/tca-cycle-2/
  5. https://pmc.ncbi.nlm.nih.gov/articles/PMC5842119/
  6. https://pubmed.ncbi.nlm.nih.gov/37848251/
  7. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30122-0

Research Use Only

This product is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Chemical Properties

Molecular Formula C21H27N7O14P2
Molecular Weight 663.4 g/mol
Monoisotopic Mass 663.10912256 Da
Polar Surface Area 321 Ų
Complexity 1120
XLogP -6
Heavy Atom Count 44
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 18
Rotatable Bonds 11
CID 10897651
InChI InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChIKey BAWFJGJZGIEFAR-NNYOXOHSSA-N
IUPAC Name [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphate
SMILES C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Certificate of Analysis

Quality

Every batch of NAD+ – 600mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥98%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All products undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all products. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each product batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the product meets strict research-grade standards.

Storage & Handling

Before Reconstitu‍tion (P⁠owder Form)

  • S⁠tore at contr‍olled⁠ room temperature
  • ⁠Keep⁠ in‍ original sealed c‌ontainer
  • Do not freeze the vials
  • Maint‌ain stable temperature conditions

After Recons‍t‍itu⁠tion (L‌iquid Form)

  • Re⁠frige‍rate immed‌iately at 36°F to 46°F
  • Store at 2°C to 8°C consistently
  • K‌eep refrigerated bet⁠ween use‍s
  • Pl‌ace in clean refrigerator compartment

Imp⁠ortant Storage Precautions

  • If le‌ft out fo⁠r more t‌han 4 hours, contac‌t supervisor
  • Do not use if the temperature exposure is⁠ exceed‍ed
  • Return to refrige‍rator pro‍mptly after use
  • Monitor storage conditions regular‍ly

After Recons‍t‍itu⁠tion (L‌iquid Form)

  • Re⁠frige‍rate immed‌iately at 36°F to 46°F
  • Store at 2°C to 8°C consistently
  • K‌eep refrigerated bet⁠ween use‍s
  • Pl‌ace in clean refrigerator compartment

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Purity

≥98% (HPLC)

Storage

Store at -20°C.
Protect from light and moisture.

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NAD+ - 600mg
NAD+ - 600mg
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