Melanotan I (MT1) – 5mg

MT-1 5mg is a synthetic linear analog of α-melanocyte-stimulating hormone (α-MSH) commonly used as an experimental peptide in laboratory investigations of melanogenesis, photoprotection, and melanocortin-1 receptor (MC1R) signaling.

$56.00

9 in stock

MT-I 5mg (Melanotan I)

Want to purchase MT-1 5mg (Melanotan I) for research purposes? MT-1 5mg is a synthetic linear analog of α-melanocyte-stimulating hormone (α-MSH) commonly used as an experimental peptide in laboratory investigations of melanogenesis, photoprotection, and melanocortin-1 receptor (MC1R) signaling. Important Research Disclaimer: MT-1 5mg is for research use only. The F.D.A. does not approve it for consumption, tanning, skin protection, or any therapeutic or cosmetic purpose. This is for research use only by qualified researchers and does not apply to in-vitro, ex-vivo, or animal work performed in controlled laboratories where this product is the test of interest. Not for human or personal use.

What is MT-1 (Melanotan I) 5mg?

Melanotan I (MT-1) is a linear peptide of 13 amino acids with the following sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂

Molecular Formula:

C₇₈H₁₁₁N₂₁O₁₉

Molecular Weight:

1646.85 Da Its selective agonism of the melanocortin-1 receptor (MC1R) present on melanocytes induces eumelanin pigmentation, the photoprotective form of melanin. Due to its cleaner overall profile compared to broader-acting analogs, MT-1 5mg is frequently selected by researchers for studies that require targeted MC1R activation.

Difference Between MT-1 5mg And MT-2

The differences between MT-1 and MT-2 are mainly structural and in receptor activity:

MT-1 (Melanotan I) is a linear 13-amino acid peptide, known for its selectivity towards MC1R and research as evidence of pigmentation and photoprotection, thus limiting off-target effects and shaping the next generation of melanocortins.
MT-2 is a cyclic heptapeptide with a lactam bridge to create greater potency, prolonged duration, but also stronger agonism on MC3R and MC4R receptors, which can result in side effects like libido increase, nausea, changes in appetite,

In preclinical research, MT-1 5mg is chosen when a targeted MC1R profile is desired and MT-2 as broader melanocortin activation.

MT-1 5mg (Melanotan I) Research-Based Benefits

MT-1 5mg has been studied in laboratory and preclinical studies for a few key areas:

Stimulation of melanin production

MT-1 binds and activates MC1R, and increases eumelanin synthesis in low-level UV exposure

Photoprotective Effects

Controlled sunburn cell studies using human volunteers demonstrated a reduction in activity (47%) of MT-1 after exposure to UV light, suggesting that the density of melanin produced acts to protect skin through greater compaction.

Increased UV Tolerance

Evidence of MT-1 holding a more extended UV window with less skin damage makes it noteworthy for photosensitivity and UV-related cellular response studies.

Support for DNA Repair and Anti-Inflammatory

MT-1 may reduce inflammation caused by UV and also help dermal cells with DNA repair.

Dermatological & Pigmentation Research

MT-1 5mg is commonly used in the research of pigmentation disorders, actinic damage protection, and melanocyte biology in controlled experimental conditions. Note : All benefits come from preclinical, animal, or limited early-phase research studies. They are not therapeutic or cosmetic claims. The research peptide form has not been established for human safety and efficacy.

Product Specifications – MT-1 5mg

Peptide: MT-1 (Melanotan I) Labeled Quantity: 5 mg lyophilized powder per vial Purity: HPLC grade (≥98% by HPLC) Form: Lyophilized for extreme stability Applications: For Laboratory Research Use Only MT-1 5mg, being a selective compound with transformative research potential advantage for exploration of melanocortin receptor signaling aspects in pigmentation pathways involving photoprotection or UV-induced cellular damage.

References

Dorr RT, et al. Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Arch Dermatol. 2004;140(7):827-835.
Böhm M. An overview of benefits and risks of chronic melanocortin-1 receptor activation. J Eur Acad Dermatol Venereol. 2024.

Ugwu SO, et al. Skin pigmentation and pharmacokinetics of melanotan-I in humans. Biopharm Drug Dispos. 1997;18(3):259-269.

Hadley ME, et al. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006;27(2):442-452.

Orion Peptides is the best choice for ultra-pure MT-1 5mg with standard Certificates of Analysis and a quick article. ALL RESEARCH PEPTIDES FOR LABORATORY USE ONLY

Research Use Only

This product is intended for laboratory research use only. It is not intended for human or animal consumption, or for use in diagnostic or therapeutic procedures.

Certificate of Analysis

Quality

Every batch of Melanotan I (MT1) – 5mg is tested for purity and identity using industry-standard methods.

HPLC Analysis

High-Performance Liquid Chromatography confirms purity ≥98%. Each batch is analyzed to ensure consistent quality.

Mass Spectrometry (MS)

Identity verification via mass spectrometry confirms correct molecular weight of 4113.58 g/mol.

Third-Party Testing

All products undergo independent third-party laboratory testing for quality assurance.

Request COA

Certificate of Analysis documents are available for all products. Contact us with your order number to request batch-specific documentation.

COA Lab Tests

Each product batch is tested by independent laboratories to verify purity, identity, and quality. The Certificate of Analysis (COA) provides transparent lab results, ensuring the product meets strict research-grade standards.

Storage & Handling

Before R⁠econstitution (Powder Form)

Not recommended for ex⁠tend⁠ed room tem⁠perature storage⁠

Long-Term Stor⁠age

Store desicc⁠a‍ted bel‌ow -20°C
Kee‌p in a moi‍sture-free environment
Use desic‌cant pa‍ck t‌o pr‍event moisture exposure
Store⁠ in original s‌ea⁠led container

Short-Term‌ Storage

Store at 4°C or 39°F
‌U‍se with‍in 2‍-7 days of the recon‍stitution‌
Keep‌ refrigerated between uses

Long-Term Stor⁠age

Store desicc⁠a‍ted bel‌ow -20°C
Kee‌p in a moi‍sture-free environment
Use desic‌cant pa‍ck t‌o pr‍event moisture exposure
Store⁠ in original s‌ea⁠led container

Melanotan I (MT1) – 5mg

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MT-I 5mg (Melanotan I)

What is MT-1 (Melanotan I) 5mg?

Molecular Formula:

Molecular Weight:

Difference Between MT-1 5mg And MT-2

MT-1 5mg (Melanotan I) Research-Based Benefits

Stimulation of melanin production

Photoprotective Effects

Increased UV Tolerance

Support for DNA Repair and Anti-Inflammatory

Dermatological & Pigmentation Research

Product Specifications – MT-1 5mg

References

Research Use Only

Certificate of Analysis

Quality

HPLC Analysis

Mass Spectrometry (MS)

Third-Party Testing

Request COA

COA Lab Tests

Storage & Handling

Before R⁠econstitution (Powder Form)

Long-Term Stor⁠age

Short-Term‌ Storage

Long-Term Stor⁠age

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